Wheat is a cereal grain cultivated around the world. It is a leading source of vegetable protein in the human diet and, after rice, is the main human food crop. Clearly, wheat is a valuable food source. As with most things in life, with the good comes some bad. Wheat is associated with a number of health issues. Among more well-known wheat-associated disorders such as allergic and autoimmune (e.g., celiac disease) are those related to increases in insulin. Wheat-induced increases in insulin are linked to a number of negative outcomes. Included in these is acne.